Discussion. HNPP is an autosomal-inherited disease associated with loss of a PMP22 gene copy, in which slight compression can cause sudden muscle weakness and sensory disturbance of monoplegia.
What does Apple plexi mean?
Apoplexy: A venerable term for a stroke, a cerebrovascular accident (CVA), often associated with loss of consciousness and paralysis of various parts of the body. The word “apoplexy” comes from the Greek “apoplexia” meaning a seizure, in the sense of being struck down.
What is cerebri Apoplexia?
2) The pathologic changes in the cerebral tissues, by either occlusion of a vessel (infarc- tion) or rupture of a vessel (haemorrhage) .
What is death by apoplexy?
From the late 14th to the late 19th century, apoplexy referred to any sudden death that began with a sudden loss of consciousness, especially one in which the victim died within a matter of seconds after losing consciousness.
What are the causes of apoplexy?
Apoplexy may be caused by:
- A tumor.
- Hormonal imbalance.
- Blood clot.
- An illness.
- Changes in blood volume or blood pressure.
- Problems with blood clotting.
How is apoplexy treated?
Acute apoplexy may require surgery to relieve pressure on the pituitary and improve vision symptoms. Severe cases need emergency surgery. If vision is not affected, surgery is often not necessary. Immediate treatment with adrenal replacement hormones (glucocorticoids) may be needed.
Is apoplexy curable?
Pituitary apoplexy is a medical emergency and can be fatal if untreated. With treatment, however, the prognosis is good. Surgery is performed after medical stabilization.
What does PEXY mean?
The combining form -pexy is used like a suffix meaning “solidity.” It is often used in medical terms, especially in surgery for procedures that fix an organ into place.
What is a common symptom of apoplexy?
The most common symptoms include sudden severe headache with nausea and vomiting, double vision or loss of vision, change in mental status, loss of eye muscle control, and meningismus (symptoms associated with irritation of the brain and spinal cord).
When was the first stroke recorded?
It was not until 1658 that Johann Jacob Wepfer, a physician practicing in Schaffhausen, Switzerland, identified the root causes of stroke. Based on postmortem examinations of people who had died of the condition, Wepfer identified two forms of stroke that modern medicine still distinguishes between today.
What does pituitary apoplexy feel like?
The word apoplexy is defined as a sudden neurologic impairment, usually due to a vascular process. Pituitary apoplexy is characterized by a sudden onset of headache, visual symptoms, altered mental status, and hormonal dysfunction due to acute hemorrhage or infarction of a pituitary gland.
What brings on a stroke?
There are two main causes of stroke: a blocked artery (ischemic stroke) or leaking or bursting of a blood vessel (hemorrhagic stroke). Some people may have only a temporary disruption of blood flow to the brain, known as a transient ischemic attack (TIA), that doesn’t cause lasting symptoms.
What is ischemic stroke?
An ischemic stroke happens when blood flow through the artery that supplies oxygen-rich blood to the brain becomes blocked. Blood clots often cause the blockages that lead to ischemic strokes.
What is Hypopituitary?
Hypopituitarism is a rare disorder in which your pituitary gland fails to produce one or more hormones, or doesn’t produce enough hormones. The pituitary gland is a kidney-bean-sized gland situated at the base of your brain.
Is pituitary apoplexy a stroke?
Pituitary apoplexy is a condition in which the pituitary tumor spontaneously hemorrhages (bleeds). The term “pituitary apoplexy” can also describe a less common condition when a pituitary tumor outgrows its blood supply (a stroke).
How common is pituitary apoplexy?
Pituitary apoplexy is a potentially life-threatening endocrine disorder which may result from either from infarction or haemorrhage in the pituitary. It has been reported with a wide range of incidence ranging from around 1% to 26% in various studies. There is slight male preponderance in most studies.
Can a pituitary gland explode?
Pituitary adenoma combined with intracranial aneurysm is not rare. Some aneurysms are located inside pituitary adenomas, and most do not rupture. Pituitary apoplexy caused by aneurysm rupture is rare and is easily misdiagnosed as simple pituitary adenoma apoplexy.
What is Sheehan’s disease?
Sheehan’s syndrome is a condition that affects women who lose a life-threatening amount of blood in childbirth or who have severe low blood pressure during or after childbirth, which can deprive the body of oxygen. This lack of oxygen that causes damage to the pituitary gland is known as Sheehan’s syndrome.
Can a pituitary tumor cause a stroke?
Clinically, pituitary apoplexy can be classified into typical stroke and subclinical stroke. Common clinical manifestations of pituitary apoplexy include acute headache, nausea, visual dysfunctions, and cranial nerve palsy and consciousness difficulty .
What is Nelson syndrome?
Nelson syndrome is a disorder characterized by abnormal hormone secretion, enlargement of the pituitary gland (hypophysis), and the development of large and invasive growths known as adenomas. It occurs in an estimated 15 to 25 percent of people who undergo surgical removal of the adrenal glands for Cushing disease.
What are the 5 warning signs of a stroke?
The five warning signs of stroke are:
- Sudden onset of weakness or numbness on one side of the body.
- Sudden speech difficulty or confusion.
- Sudden difficulty seeing in one or both eyes.
- Sudden onset of dizziness, trouble walking or loss of balance.
- Sudden, severe headache with no known cause.
How might someone who is apoplectic behave?
Someone who is apoplectic is not just mad — they’re so filled with rage, they can barely communicate. … When this happens, a person becomes apoplectic. This word also applies to someone who acts so upset, it is like he or she is having a stroke.
What are the early warning signs of a stroke?
- Numbness or weakness in your face, arm, or leg, especially on one side.
- Confusion or trouble understanding other people.
- Difficulty speaking.
- Trouble seeing with one or both eyes.
- Problems walking or staying balanced or coordinated.
- Severe headache that comes on for no reason.